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Welcome to xanaxwholesale.com, your one-stop destination for buying Xanax online and having it conveniently delivered to your doorstep. We understand the importance of a reliable and efficient service when it comes to purchasing medications, especially for those in need of anxiety relief. At Xanax wholesale, we prioritize your satisfaction and convenience, offering free, fast, and discreet delivery. With our expertise and commitment to quality, you can trust us to provide a seamless experience, ensuring you receive the medication you need, when you need it.

WARNING!

  1. Shipping is strictly limited within USA, Canada and the EU. We do not ship Xanax out of these areas.
  2. As part of our commitment to safe and responsible use, you must be 21 years of age or above to purchase anything from this site. 
  3. We do not ship on weekends and holidays. We only ship xanax from Mondays to Fridays between 8:00 am to 17:00 pm

Specification for Xanax (Alprazolam)

General Information

  • Brand Name: Xanax
  • Generic Name: Alprazolam
  • Drug Class: Benzodiazepine
  • Mechanism of Action: Binds to GABA receptors in the brain to produce a calming effect

Indications

  • Treatment of anxiety disorders
  • Management of panic disorders, with or without agoraphobia

Dosage Forms and Strengths

  • Tablets:
    • 0.25 mg
    • 0.5 mg
    • 1 mg
    • 2 mg
  • Extended-Release Tablets:
    • 0.5 mg
    • 1 mg
    • 2 mg
    • 3 mg
  • Oral Solution:
    • 1 mg/mL

Pharmacokinetics

  • Absorption: Rapidly absorbed with peak plasma concentrations occurring within 1 to 2 hours.
  • Distribution: Highly bound to plasma proteins.
  • Metabolism: Metabolized in the liver, primarily by cytochrome P450 3A (CYP3A) enzymes.
  • Elimination: Excreted primarily in the urine, with an average half-life of 11.2 hours (range: 6.3 to 26.9 hours).

Administration

  • Initial Dosage for Anxiety: 0.25 mg to 0.5 mg administered three times daily.
  • Initial Dosage for Panic Disorder: 0.5 mg three times daily.
  • Maintenance Dosage: The dose may be adjusted at intervals of 3 to 4 days in increments of no more than 1 mg/day.
  • Maximum Dosage: Should not exceed 4 mg/day in divided doses.

Contraindications

  • Known sensitivity to benzodiazepines
  • Acute narrow-angle glaucoma
  • Concurrent use with ketoconazole or itraconazole

Warnings and Precautions

  • Dependency and Abuse: Xanax has a high potential for abuse and dependence. Use with caution in patients with a history of substance abuse.
  • CNS Depression: May cause sedation, dizziness, and decreased coordination. Caution patients against engaging in hazardous activities requiring mental alertness.
  • Withdrawal: Gradual tapering is recommended to avoid withdrawal symptoms.
  • Use in Pregnancy: Category D. Risk of congenital abnormalities; use only if clearly needed and benefits outweigh the risks.
  • Geriatric Use: Lower doses are recommended due to increased sensitivity.

Adverse Reactions

  • Common: Drowsiness, light-headedness, dizziness, dry mouth, and changes in sex drive/ability.
  • Serious: Seizures, hallucinations, severe skin reactions, and jaundice.

Drug Interactions

  • CNS Depressants: Enhanced sedation with other CNS depressants (e.g., alcohol, opioids).
  • Inhibitors of CYP3A: Increased plasma levels with CYP3A inhibitors (e.g., ketoconazole, erythromycin).
  • Inducers of CYP3A: Decreased plasma levels with CYP3A inducers (e.g., carbamazepine, phenytoin).

Storage and Handling

  • Storage Conditions: Store at 20°C to 25°C (68°F to 77°F). Protect from light and moisture.
  • Handling Precautions: Handle with care. Follow standard procedures for disposal.

Patient Counseling Information

  • Advise patients on the risks of dependency and to take the medication exactly as prescribed.
  • Instruct patients to avoid alcohol and other CNS depressants.
  • Warn patients about the potential for impaired ability to perform tasks requiring mental alertness.
  • Inform pregnant women of the potential risk to the fetus and advise on alternative treatment options.

Manufacturer Information

  • Manufacturer: [Manufacturer’s Name]
  • Contact Information: [Manufacturer’s Contact Information]

Approval and Regulatory Status

  • FDA Approval Date: [FDA Approval Date]
  • Marketing Authorization Number: [Authorization Number]

Clinical Studies

  • Summary of key clinical trials demonstrating efficacy and safety in anxiety and panic disorders.

References

  • Comprehensive list of references including clinical trial data, pharmacological studies, and official guidelines.

This specification serves as a comprehensive guide to the use, dosage, pharmacokinetics, and safety of Xanax (Alprazolam). Ensure all healthcare professionals prescribing this medication are familiar with its contents.

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