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Important Safety Information and Indications

What is the most important information I should know about XANAX?

XANAX is a benzodiazepine medication. Taking it with opioid medications, alcohol, or other central nervous system depressants (including street drugs) can cause severe drowsiness, breathing problems (respiratory depression), coma, and death.

Seek emergency help immediately if you experience:

  • Shallow or slowed breathing
  • Breathing stops (which may lead to the heart stopping)
  • Excessive sleepiness (sedation)

Avoid driving or operating heavy machinery until you understand how XANAX affects you, especially when taken with opioids.

There is a risk of abuse, misuse, and addiction with XANAX, which can lead to overdose and serious side effects including coma, death, delirium, paranoia, suicidal thoughts or actions, seizures, and difficulty breathing. Addiction can occur even when taking XANAX as prescribed.

XANAX can cause physical dependence and withdrawal reactions. Do not stop taking XANAX suddenly, as it can lead to serious and life-threatening side effects such as unusual movements, responses, or expressions, seizures, severe mental or nervous system changes, depression, hallucinations, extreme increases in activity or talking, losing touch with reality, and suicidal thoughts or actions.

CALL YOUR HEALTHCARE PROVIDER OR GO TO THE HOSPITAL EMERGENCY ROOM IMMEDIATELY IF YOU EXPERIENCE ANY OF THE ABOVE SERIOUS SIDE EFFECTS.

XANAX is a federally controlled substance (C-IV) because it can be abused or lead to dependence. Store it safely to prevent misuse and abuse. The safety and effectiveness of XANAX in children are not established.

Do not take XANAX if you are allergic to alprazolam, other benzodiazepines, or any ingredients in XANAX. Avoid XANAX if you are on antifungal treatments like ketoconazole or itraconazole.

Before taking XANAX, inform your healthcare provider if you:

  • Have or have had depression, mood problems, or suicidal thoughts or behavior
  • Have liver or kidney problems
  • Have lung disease or breathing problems
  • Are pregnant or plan to become pregnant. Taking XANAX late in pregnancy may cause your baby to have symptoms of sedation and/or withdrawal. Notify your healthcare provider if you become or think you are pregnant during treatment.
  • Are breastfeeding or plan to breastfeed. XANAX passes into breast milk, so breastfeeding is not recommended during treatment.

Inform your healthcare provider about all the medicines you take, including:

  • Prescription and over-the-counter medicines
  • Vitamins
  • Herbal supplements

Taking XANAX with certain other medicines can cause side effects or affect how well XANAX or the other medicines work. Do not start or stop other medicines without consulting your healthcare provider.

Instructions for taking XANAX:

  • Follow your healthcare provider’s prescription exactly.
  • Do not take more XANAX than prescribed or for a longer duration than prescribed.
  • Do not share XANAX with others.
  • Store XANAX safely and keep it out of reach of children.

Potential serious side effects of XANAX:

  • Seizures. Stopping XANAX can cause seizures, including those that do not stop (status epilepticus).
  • Mania. XANAX may cause increased activity and talking (hypomania and mania) in people with depression.

XANAX can cause drowsiness, dizziness, and slow your thinking and motor skills. Do not drive, operate heavy machinery, or engage in dangerous activities until you know how XANAX affects you. Avoid alcohol and other drugs that cause drowsiness or dizziness while taking XANAX without first consulting your healthcare provider, as it can worsen these effects.

Common side effects of XANAX include:

  • Coordination problems
  • Low blood pressure (hypotension)
  • Difficulty speaking clearly
  • Changes in sex drive (libido)

Indications

XANAX (alprazolam) is prescribed for the treatment of anxiety disorders and for the short-term relief of anxiety symptoms. It is also indicated for the treatment of panic disorder with or without agoraphobia (fear of places and situations that might cause panic, helplessness, or embarrassment).

Please refer to the Full Prescribing Information, including the BOXED WARNING, and Medication Guide for more details.